Tomas A. Prolla : rechercher sur Z-Library

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1

Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction

Shinichi Someya, Wei Yu, William C. Hallows, Jinze Xu, James M. Vann, Christiaan Leeuwenburgh, Masaru Tanokura, John M. Denu, Tomas A. Prolla

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 850 KB

english, 2010

2

Mitochondrial point mutations do not limit the natural lifespan of mice

Vermulst, Marc, Bielas, Jason H, Kujoth, Gregory C, Ladiges, Warren C, Rabinovitch, Peter S, Prolla, Tomas A, Loeb, Lawrence A

Journal:

Nature Genetics

Année:

2007

Langue:

english

Fichier:

PDF, 169 KB

english, 2007

3

Caloric restriction suppresses apoptotic cell death in the mammalian cochlea and leads to prevention of presbycusis

Shinichi Someya, Tatsuya Yamasoba, Richard Weindruch, Tomas A. Prolla, Masaru Tanokura

Journal:

Neurobiology of Aging

Année:

2007

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2007

4

Molecular mechanisms of brain aging and neurodegenerative disorders: lessons from dietary restriction

Tomas A Prolla, Mark P Mattson

Journal:

Trends in Neurosciences

Année:

2001

Langue:

english

Fichier:

PDF, 352 KB

english, 2001

5

Dynamic regulation of PGC-1α localization and turnover implicates mitochondrial adaptation in calorie restriction and the stress response

Rozalyn M. Anderson, Jamie L. Barger, Michael G. Edwards, Kristina H. Braun, Clare E. O’Connor, Tomas A. Prolla, Richard Weindruch

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2008

6

Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair

Strand, Micheline, Prolla, Tomas A., Liskay, R. Michael, Petes, Thomas D.

Journal:

Année:

1993

Fichier:

PDF, 456 KB

1993

7

Impairment of the Transcriptional Responses to Oxidative Stress in the Heart of Aged C57BL/6 Mice

MICHAEL G. EDWARDS, DEEPAYAN SARKAR, ROGER KLOPP, JASON D. MORROW, RICHARD WEINDRUCH, TOMAS A. PROLLA

Journal:

Annals of the New York Academy of Sciences

Année:

2004

Fichier:

PDF, 1.38 MB

2004

8

The emerging role of iron dyshomeostasis in the mitochondrial decay of aging

Jinze Xu, Emanuele Marzetti, Arnold Y. Seo, Jae-Sung Kim, Tomas A. Prolla, Christiaan Leeuwenburgh

Journal:

Mechanisms of Ageing and Development

Année:

2010

Langue:

english

Fichier:

PDF, 219 KB

english, 2010

9

The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults

Levi J Yant, Qitao Ran, Lin Rao, Holly Van Remmen, Toru Shibatani, Jason G Belter, Lucia Motta, Arlan Richardson, Tomas A Prolla

Journal:

Free Radical Biology and Medicine

Année:

2003

Langue:

english

Fichier:

PDF, 223 KB

english, 2003

10

The mtDNA Mutation Spectrum of the Progeroid Polg Mutator Mouse Includes Abundant Control Region Multimers

Siôn L. Williams, Jia Huang, Yvonne J.K. Edwards, Rick H. Ulloa, Lloye M. Dillon, Tomas A. Prolla, Jeffery M. Vance, Carlos T. Moraes, Stephan Züchner

Journal:

Cell Metabolism

Année:

2010

Langue:

english

Fichier:

PDF, 760 KB

english, 2010

11

Role of mitochondrial dysfunction and mitochondrial DNA mutations in age-related hearing loss

Tatsuya Yamasoba, Shinichi Someya, Chikako Yamada, Richard Weindruch, Tomas A. Prolla, Masaru Tanokura

Journal:

Hearing Research

Année:

2007

Langue:

english

Fichier:

PDF, 1021 KB

english, 2007

12

121 Mitochondrial aging countermeasure—Endurance exercise confers complete phenotypic protection in PolG mutator mouse

Adeel Safdar, Arkan Abadi, Mahmood Akhtar, Gregory C. Kujoth, Tomas A. Prolla, Bart P. Hettinga, Mark A. Tarnopolsky

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 56 KB

english, 2010

13

The effect of increased mitochondrial biogenesis on premature aging

Lloye M. Dillon⁎, Tomas A. Prolla, Carlos T. Moraes

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 58 KB

english, 2011

14

Mitochondrial DNA mutations provide selective advantage in hematopoietic stem cell niche

Michael L. Chen, T. Daniel Logan, Maryann Hochberg, Gregory E. Wilding, Wei Tan, Gregory Kujoth, Tomas A. Prolla, Martin Carroll, James E. Thompson⁎

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 58 KB

english, 2011

15

Endurance exercise reduces mitochondrial DNA random point mutations and reverses the premature aging transcriptome in PolG mutator mouse: I believe in miracle!

Adeel Safdar⁎, Simon Melov, Mahmood Akhtar, Gregory C. Kujoth, Tomas A. Prolla, Bart P. Hettinga, Mark A. Tarnopolsky

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 74 KB

english, 2011

16

The role of mtDNA mutations in the pathogenesis of age-related hearing loss in mice carrying a mutator DNA polymerase γ

Shinichi Someya, Tatsuya Yamasoba, Gregory C. Kujoth, Thomas D. Pugh, Richard Weindruch, Masaru Tanokura, Tomas A. Prolla

Journal:

Neurobiology of Aging

Année:

2008

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2008

17

Behavioral and metabolic characterization of heterozygous and homozygous POLG mutator mice

Dai, Ying, Kiselak, Tomas, Clark, Joanne, Clore, Elizabeth, Zheng, Kangni, Cheng, Allen, Kujoth, Gregory C., Prolla, Tomas A., Maratos-Flier, Eleftheria, Simon, David K.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2013

18

Microarray Profiling of Gene Expression in Aging and Its Alteration by Caloric Restriction in Mice

Weindruch, Richard, Kayo, Tsuyoshi, Lee, Cheol-Koo, Prolla, Tomas A.

Journal:

Journal of Nutrition

Année:

2001

Langue:

english

Fichier:

PDF, 209 KB

english, 2001

19

Effects of calorie restriction on the lifespan and healthspan of POLG mitochondrial mutator mice

Someya, Shinichi, Kujoth, Gregory C., Kim, Mi-Jung, Hacker, Timothy A., Vermulst, Marc, Weindruch, Richard, Prolla, Tomas A., Kato, Tadafumi

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 1.89 MB

english, 2017

20

Energy Restriction Lowers the Expression of Genes Linked to Inflammation, the Cytoskeleton, the Extracellular Matrix, and Angiogenesis in Mouse Adipose Tissue

Higami, Yoshikazu, Barger, Jamie L., Page, Grier P., Allison, David B., Smith, Steven R., Prolla, Tomas A., Weindruch, Richard

Journal:

Journal of Nutrition

Année:

2006

Langue:

english

Fichier:

PDF, 7.89 MB

english, 2006

21

Caloric Intake, Oxidative Stress and Aging

Lee, Cheol Koo, Prolla, Tomas A., Weindruch, Richard

Journal:

The Scientific World JOURNAL

Année:

2001

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2001

22

13 C NMR visibility of rabbit muscle glycogen in vivo

Rolf Gruetter, Tomas A. Prolla, Robert G. Shulman

Journal:

Magnetic Resonance in Medicine

Année:

1991

Langue:

english

Fichier:

PDF, 368 KB

english, 1991

23

Synthesis of protodolomite from coral reef sand

Hiroyuki Fujimura, Tamotsu Oomori, Shigeru Kochi, Tomas A. Prolla, Shinichi Someya

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 129 KB

english, 2006

24

A mixture model approach for the analysis of microarray gene expression data

David B. Allison, Gary L. Gadbury, Moonseong Heo, José R. Fernández, Cheol-Koo Lee, Tomas A. Prolla, Richard Weindruch

Journal:

Computational Statistics & Data Analysis

Année:

2002

Langue:

english

Fichier:

PDF, 266 KB

english, 2002

25

A novel method for biodosimetry

Wael Abdel Megid, Martin G. Ensenberger, Richard B. Halberg, Stephen A. Stanhope, Marijo G. Kent-First, Tomas A. Prolla, Jeff W. Bacher

Journal:

Radiation and Environmental Biophysics

Année:

2007

Langue:

english

Fichier:

PDF, 405 KB

english, 2007

26

Altered lipid metabolism in rodents subjected to calorie restriction

Yoshikazu Higami, Richard Weindruch, Tomas A Prolla, Isao Shimokawa

Journal:

Geriatrics & Gerontology International

Année:

2004

Langue:

english

Fichier:

PDF, 42 KB

english, 2004

27

Gene expression profiling of aging in multiple mouse strains: identification of aging biomarkers and impact of dietary antioxidants

Sang-Kyu Park, Kyoungmi Kim, Grier P. Page, David B. Allison, Richard Weindruch, Tomas A. Prolla

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 438 KB

english, 2009

28

Age-dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria

Dao-Fu Dai, Tony Chen, Jonathan Wanagat, Michael Laflamme, David J. Marcinek, Mary J Emond, Calvin P. Ngo, Tomas A. Prolla, Peter S. Rabinovitch

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 568 KB

english, 2010

29

The Shc locus regulates insulin signaling and adiposity in mammals

Alexey A. Tomilov, Jon J. Ramsey, Kevork Hagopian, Marco Giorgio, Kyoungmi M. Kim, Adam Lam, Enrica Migliaccio, Kent C. Lloyd, Ina Berniakovich, Tomas A. Prolla, PierGiuseppe Pelicci, Gino A. Cortopas

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 452 KB

english, 2011

30

10.1038/35023

Prolla, Tomas A.

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 368 KB

english, 1998

31

10.1038/35022743

Prolla, Tomas A.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 48 KB

english, 2000

32

10.1038/77046

Weindruch, Richard, Prolla, Tomas A., Lee, Cheol-Koo

Journal:

Nature Genetics

Année:

2000

Langue:

english

Fichier:

PDF, 94 KB

english, 2000

33

DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice

Vermulst, Marc, Wanagat, Jonathan, Kujoth, Gregory C, Bielas, Jason H, Rabinovitch, Peter S, Prolla, Tomas A, Loeb, Lawrence A

Journal:

Nature Genetics

Année:

2008

Langue:

english

Fichier:

PDF, 334 KB

english, 2008

34

Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DMA mismatch repair

Prolla, Tomas A., Baker, Sean M., Harris, Allie C., Tsao, Jen-Lan, Yao, Xiang, Bronner, C. Eric, Zheng, Binhai, Gordon, Melissa, Reneker, Jeffrey, Arnheim, Norman

Journal:

Nature Genetics

Année:

1998

Fichier:

PDF, 515 KB

1998

35

Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over

Baker, Sean M., Plug, Annemieke W., Prolla, Tomas A., Bronner, C. Eric, Harris, Allie C., Yao, Xiang, Christie, Donna-Marie, Monell, Craig, Arnheim, Norm, Bradley, Allan

Journal:

Nature Genetics

Année:

1996

Fichier:

PDF, 1.00 MB

1996

36

Vitamin E and Gene Expression in Immune Cells

SUNG NIM HAN, OSKAR ADOLFSSON, CHEOL-KOO LEE, TOMAS A. PROLLA, JOSE ORDOVAS, SIMIN NIKBIN MEYDANI

Journal:

Annals of the New York Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 820 KB

english, 2004

37

DNA mismatch repair deficient mice in cancer research

Tomas A. Prolla, Alejandro Abuin, Allan Bradley

Journal:

Seminars in Cancer Biology

Année:

1996

Langue:

english

Fichier:

PDF, 76 KB

english, 1996

38

Gene expression profiling reveals differential effects of sodium selenite, selenomethionine, and yeast-derived selenium in the mouse

Jamie L. Barger, Tsuyoshi Kayo, Thomas D. Pugh, James A. Vann, Ronan Power, Karl Dawson, Richard Weindruch, Tomas A. Prolla

Journal:

Genes & Nutrition

Année:

2012

Langue:

english

Fichier:

PDF, 767 KB

english, 2012

39

Genes encoding mitochondrial respiratory chain components are profoundly down-regulated with aging in the cochlea of DBA/2J mice

Shinichi Someya, Tatsuya Yamasoba, Tomas A. Prolla, Masaru Tanokura

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 511 KB

english, 2007

40

Evaluation of sex differences on mitochondrial bioenergetics and apoptosis in mice

Alberto Sanz, Asimina Hiona, Gregory C. Kujoth, Arnold Y. Seo, Tim Hofer, Evelyn Kouwenhoven, Rizwan Kalani, Tomas A. Prolla, Gustavo Barja, Christiaan Leeuwenburgh

Journal:

Experimental Gerontology

Année:

2007

Langue:

english

Fichier:

PDF, 197 KB

english, 2007

41

Evolving insight into the role of mitochondrial DNA mutations in aging

Gregory C. Kujoth, Tomas A. Prolla

Journal:

Experimental Gerontology

Année:

2008

Langue:

english

Fichier:

PDF, 195 KB

english, 2008

42

The impact of α-lipoic acid, coenzyme Q10 and caloric restriction on life span and gene expression patterns in mice

Cheol-Koo Lee, Thomas D Pugh, Roger G Klopp, Jode Edwards, David B Allison, Richard Weindruch, Tomas A Prolla

Journal:

Free Radical Biology and Medicine

Année:

2004

Langue:

english

Fichier:

PDF, 325 KB

english, 2004

43

Multiple roads to the aging phenotype: insights from the molecular dissection of progerias through DNA microarray analysis

Tomas A. Prolla

Journal:

Mechanisms of Ageing and Development

Année:

2005

Langue:

english

Fichier:

PDF, 157 KB

english, 2005

44

Mitochondria and aging

Tomas A. Prolla, Vilhelm A. Bohr, Nadja C. de Souza-Pinto

Journal:

Mechanisms of Ageing and Development

Année:

2010

Langue:

english

Fichier:

PDF, 61 KB

english, 2010

45

Mitochondrial oxidative damage and apoptosis in age-related hearing loss

Shinichi Someya, Tomas A. Prolla

Journal:

Mechanisms of Ageing and Development

Année:

2010

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2010

46

Gene expression profiling of aging using DNA microarrays

Richard Weindruch, Tsuyoshi Kayo, Cheol-Koo Lee, Tomas A. Prolla

Journal:

Mechanisms of Ageing and Development

Année:

2002

Langue:

english

Fichier:

PDF, 862 KB

english, 2002

47

Embryonic fibroblasts from Gpx4+/− mice: a novel model for studying the role of membrane peroxidation in biological processes

Qitao Ran, Holly Van Remmen, Mingjun Gu, Wenbo Qi, L.Jackson Roberts II, Tomas Prolla, Arlan Richardson

Journal:

Free Radical Biology and Medicine

Année:

2003

Langue:

english

Fichier:

PDF, 276 KB

english, 2003

48

Gene expression profiling of aging reveals activation of a p53-mediated transcriptional program

Michael G Edwards, Rozalyn M Anderson, Ming Yuan, Christina M Kendziorski, Richard Weindruch, Tomas A Prolla

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 394 KB

english, 2007

49

A Photochemical System for Generating Free Radicals: Superoxide, Phenoxyl, Ferryl and Methyl

Prolla, Tomas A., Mehlhorn, Rolf J.

Journal:

Free Radical Research

Année:

1990

Langue:

english

Fichier:

PDF, 623 KB

english, 1990

50

Lessons learned from gene expression profile studies of aging and caloric restriction

Sang-Kyu Park, Tomas A. Prolla

Journal:

Ageing Research Reviews

Année:

2005

Langue:

english

Fichier:

PDF, 117 KB

english, 2005